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Effect of IgA Aggregates on Transforming Growth Factor-β1 Production in Human Mesangial Cells and the Intraglomerular Expression of Transforming Growth Factor-β1 in Patients with IgA Nephropathy

BACKGROUND: Transforming growth factor-β (TGF-β) stimulates renal fibrosis in various renal diseases including IgA nephropathy. METHODS: We examined whether immunoglobulin A (IgA) stimulated TGF-β1 synthesis in human mesangial cells (MCs), and whether this effect was mediated through the protein kin...

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Detalles Bibliográficos
Autores principales:	Han, Sang-Youb, Ihm, Chun-Gyoo, Cha, Dae-Ryong, Kang, Young-Sun, Han, Kum-Hyun, Kim, Hyoung-Kyu, Han, Jee-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Association of Internal Medicine 2005
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891411/ https://www.ncbi.nlm.nih.gov/pubmed/15906952 http://dx.doi.org/10.3904/kjim.2005.20.1.40

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