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Electron Tomography and Simulation of Baculovirus Actin Comet Tails Support a Tethered Filament Model of Pathogen Propulsion

Several pathogens induce propulsive actin comet tails in cells they invade to disseminate their infection. They achieve this by recruiting factors for actin nucleation, the Arp2/3 complex, and polymerization regulators from the host cytoplasm. Owing to limited information on the structural organizat...

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Detalles Bibliográficos
Autores principales: Mueller, Jan, Pfanzelter, Julia, Winkler, Christoph, Narita, Akihiro, Le Clainche, Christophe, Nemethova, Maria, Carlier, Marie-France, Maeda, Yuichiro, Welch, Matthew D., Ohkawa, Taro, Schmeiser, Christian, Resch, Guenter P., Small, J. Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891563/
https://www.ncbi.nlm.nih.gov/pubmed/24453943
http://dx.doi.org/10.1371/journal.pbio.1001765