Sphingosine-1-phosphate-Mediated Mobilization of Hematopoietic Stem/Progenitor Cells during Intravascular Hemolysis Requires Attenuation of SDF-1-CXCR4 Retention Signaling in Bone Marrow

Sphingosine-1-phosphate (S1P) is a crucial chemotactic factor in peripheral blood (PB) involved in the mobilization process and egress of hematopoietic stem/progenitor cells (HSPCs) from bone marrow (BM). Since S1P is present at high levels in erythrocytes, one might assume that, by increasing the p...

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Detalles Bibliográficos
Autores principales: Mierzejewska, Kasia, Klyachkin, Yuri M., Ratajczak, Janina, Abdel-Latif, Ahmed, Kucia, Magda, Ratajczak, Mariusz Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891619/
https://www.ncbi.nlm.nih.gov/pubmed/24490172
http://dx.doi.org/10.1155/2013/814549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891619/
https://www.ncbi.nlm.nih.gov/pubmed/24490172
http://dx.doi.org/10.1155/2013/814549

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