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Sphingosine-1-phosphate-Mediated Mobilization of Hematopoietic Stem/Progenitor Cells during Intravascular Hemolysis Requires Attenuation of SDF-1-CXCR4 Retention Signaling in Bone Marrow
Sphingosine-1-phosphate (S1P) is a crucial chemotactic factor in peripheral blood (PB) involved in the mobilization process and egress of hematopoietic stem/progenitor cells (HSPCs) from bone marrow (BM). Since S1P is present at high levels in erythrocytes, one might assume that, by increasing the p...
Autores principales: | Mierzejewska, Kasia, Klyachkin, Yuri M., Ratajczak, Janina, Abdel-Latif, Ahmed, Kucia, Magda, Ratajczak, Mariusz Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891619/ https://www.ncbi.nlm.nih.gov/pubmed/24490172 http://dx.doi.org/10.1155/2013/814549 |
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