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The Sphingolipid Receptor S1PR2 Is a Receptor for Nogo-A Repressing Synaptic Plasticity

Nogo-A is a membrane protein of the central nervous system (CNS) restricting neurite growth and synaptic plasticity via two extracellular domains: Nogo-66 and Nogo-A-Δ20. Receptors transducing Nogo-A-Δ20 signaling remained elusive so far. Here we identify the G protein-coupled receptor (GPCR) sphing...

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Detalles Bibliográficos
Autores principales: Kempf, Anissa, Tews, Bjoern, Arzt, Michael E., Weinmann, Oliver, Obermair, Franz J., Pernet, Vincent, Zagrebelsky, Marta, Delekate, Andrea, Iobbi, Cristina, Zemmar, Ajmal, Ristic, Zorica, Gullo, Miriam, Spies, Peter, Dodd, Dana, Gygax, Daniel, Korte, Martin, Schwab, Martin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891622/
https://www.ncbi.nlm.nih.gov/pubmed/24453941
http://dx.doi.org/10.1371/journal.pbio.1001763