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Androgen receptor activation by polychlorinated biphenyls: Epigenetic effects mediated by the histone demethylase Jarid1b

The exposure to environmental endocrine disrupting compounds (EDC), as polychlorinated biphenyls (PCBs), widely diffused in the environment may produce epigenetic changes that affect the endocrine system. We found that PCBs activate AR transcriptional activity and that this effect is potentiated by...

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Detalles Bibliográficos
Autores principales: Casati, Lavinia, Sendra, Ramon, Poletti, Angelo, Negri-Cesi, Paola, Celotti, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891687/
https://www.ncbi.nlm.nih.gov/pubmed/23907094
http://dx.doi.org/10.4161/epi.25811