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Coordinate H3K9 and DNA methylation silencing of ZNFs in toxicant-induced malignant transformation

Genome-wide disruption of the epigenetic code is a hallmark of malignancy that encompasses many distinct, highly interactive modifications. Delineating the aberrant epigenome produced during toxicant-mediated malignant transformation will help identify the underlying epigenetic drivers of environmen...

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Detalles Bibliográficos
Autores principales: Severson, Paul L, Tokar, Erik J, Vrba, Lukas, Waalkes, Michael P, Futscher, Bernard W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891689/
https://www.ncbi.nlm.nih.gov/pubmed/23974009
http://dx.doi.org/10.4161/epi.25926