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Coordinate H3K9 and DNA methylation silencing of ZNFs in toxicant-induced malignant transformation
Genome-wide disruption of the epigenetic code is a hallmark of malignancy that encompasses many distinct, highly interactive modifications. Delineating the aberrant epigenome produced during toxicant-mediated malignant transformation will help identify the underlying epigenetic drivers of environmen...
Autores principales: | Severson, Paul L, Tokar, Erik J, Vrba, Lukas, Waalkes, Michael P, Futscher, Bernard W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891689/ https://www.ncbi.nlm.nih.gov/pubmed/23974009 http://dx.doi.org/10.4161/epi.25926 |
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