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Ubiquitin-Specific Protease 5 Is Required for the Efficient Repair of DNA Double-Strand Breaks

During the DNA damage response (DDR), ubiquitination plays an important role in the recruitment and regulation of repair proteins. However, little is known about elimination of the ubiquitination signal after repair is completed. Here we show that the ubiquitin-specific protease 5 (USP5), a deubiqui...

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Detalles Bibliográficos
Autores principales: Nakajima, Satoshi, Lan, Li, Wei, Leizhen, Hsieh, Ching-Lung, Rapić-Otrin, Vesna, Yasui, Akira, Levine, Arthur S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891734/
https://www.ncbi.nlm.nih.gov/pubmed/24454762
http://dx.doi.org/10.1371/journal.pone.0084899