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A Flagellin-Derived Toll-Like Receptor 5 Agonist Stimulates Cytotoxic Lymphocyte-Mediated Tumor Immunity

Toll-like receptor (TLR) mediated recognition of pathogen associated molecular patterns allows the immune system to rapidly respond to a pathogenic insult. The “danger context” elicited by TLR agonists allows an initially non-immunogenic antigen to become immunogenic. This ability to alter environme...

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Detalles Bibliográficos
Autores principales: Leigh, Nicholas D., Bian, Guanglin, Ding, Xilai, Liu, Hong, Aygun-Sunar, Semra, Burdelya, Lyudmila G., Gudkov, Andrei V., Cao, Xuefang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891810/
https://www.ncbi.nlm.nih.gov/pubmed/24454895
http://dx.doi.org/10.1371/journal.pone.0085587