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Thioredoxin 1 as a serum marker for breast cancer and its use in combination with CEA or CA15-3 for improving the sensitivity of breast cancer diagnoses

BACKGROUND: The human cytosolic thioredoxin (Trx) contains a redox-active dithiol moiety in its conserved active-site sequence. Activation by a wide variety of stimuli leads to secretion of this cytoplasmic protein. Function of Trx1 has been implicated in regulating cell proliferation, differentiati...

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Detalles Bibliográficos
Autores principales: Park, Byung-Joon, Cha, Mee-Kyung, Kim, Il-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891982/
https://www.ncbi.nlm.nih.gov/pubmed/24393391
http://dx.doi.org/10.1186/1756-0500-7-7