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Global dynamic optimization approach to predict activation in metabolic pathways

BACKGROUND: During the last decade, a number of authors have shown that the genetic regulation of metabolic networks may follow optimality principles. Optimal control theory has been succesfully used to compute optimal enzyme profiles considering simple metabolic pathways. However, applying this opt...

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Detalles Bibliográficos
Autores principales: de Hijas-Liste, Gundián M, Klipp, Edda, Balsa-Canto, Eva, Banga, Julio R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892042/
https://www.ncbi.nlm.nih.gov/pubmed/24393148
http://dx.doi.org/10.1186/1752-0509-8-1