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Global dynamic optimization approach to predict activation in metabolic pathways
BACKGROUND: During the last decade, a number of authors have shown that the genetic regulation of metabolic networks may follow optimality principles. Optimal control theory has been succesfully used to compute optimal enzyme profiles considering simple metabolic pathways. However, applying this opt...
Autores principales: | de Hijas-Liste, Gundián M, Klipp, Edda, Balsa-Canto, Eva, Banga, Julio R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892042/ https://www.ncbi.nlm.nih.gov/pubmed/24393148 http://dx.doi.org/10.1186/1752-0509-8-1 |
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