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HERV-W polymorphism in chromosome X is associated with multiple sclerosis risk and with differential expression of MSRV

BACKGROUND: Multiple Sclerosis (MS) is an autoimmune demyelinating disease that occurs more frequently in women than in men. Multiple Sclerosis Associated Retrovirus (MSRV) is a member of HERV-W, a multicopy human endogenous retroviral family repeatedly implicated in MS pathogenesis. MSRV envelope p...

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Detalles Bibliográficos
Autores principales: García-Montojo, Marta, de la Hera, Belén, Varadé, Jezabel, de la Encarnación, Ana, Camacho, Iris, Domínguez-Mozo, María, Arias-Leal, Ana, García-Martínez, Ángel, Casanova, Ignacio, Izquierdo, Guillermo, Lucas, Miguel, Fedetz, Maria, Alcina, Antonio, Arroyo, Rafael, Matesanz, Fuencisla, Urcelay, Elena, Alvarez-Lafuente, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892049/
https://www.ncbi.nlm.nih.gov/pubmed/24405691
http://dx.doi.org/10.1186/1742-4690-11-2