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Parthenolide induces apoptosis via TNFRSF10B and PMAIP1 pathways in human lung cancer cells

BACKGROUND: Parthenolide (PTL) is a sesquiterpene lactone which can induce apoptosis in cancer cells and eradicate cancer stem cells such as leukemia stem cells, prostate tumor-initiating cells and so on. However, the mechanism remains largely unclear. METHODS: Lung cancer cells were treated with pa...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaofei, Liu, Xiangguo, Su, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892099/
https://www.ncbi.nlm.nih.gov/pubmed/24387758
http://dx.doi.org/10.1186/1756-9966-33-3