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CD56(neg)CD16(+) NK cells are activated mature NK cells with impaired effector function during HIV-1 infection

BACKGROUND: A subset of CD3(neg)CD56(neg)CD16(+) Natural Killer (NK) cells is highly expanded during chronic HIV-1 infection. The role of this subset in HIV-1 pathogenesis remains unclear. The lack of NK cell lineage-specific markers has complicated the study of minor NK cell subpopulations. RESULTS...

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Detalles Bibliográficos
Autores principales: Milush, Jeffrey M, López-Vergès, Sandra, York, Vanessa A, Deeks, Steven G, Martin, Jeffrey N, Hecht, Frederick M, Lanier, Lewis L, Nixon, Douglas F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892122/
https://www.ncbi.nlm.nih.gov/pubmed/24351015
http://dx.doi.org/10.1186/1742-4690-10-158