Cargando…

The mTOR signaling pathway regulates pain-related synaptic plasticity in rat entorhinal-hippocampal pathways

BACKGROUND: Our previous work demonstrated that persistent peripheral nociception (PPN) leads to synaptic plasticity and functional changes in the rat hippocampus. The protein kinase mTOR is a critical regulator of protein synthesis-dependent synaptic plasticity in the hippocampus as well as synapti...

Descripción completa

Detalles Bibliográficos
Autores principales: Lyu, Dan, Yu, Wenli, Tang, Ning, Wang, Ruirui, Zhao, Zhenyu, Xie, Fang, He, Yongjin, Du, Hongyin, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892125/
https://www.ncbi.nlm.nih.gov/pubmed/24313960
http://dx.doi.org/10.1186/1744-8069-9-64