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The mTOR signaling pathway regulates pain-related synaptic plasticity in rat entorhinal-hippocampal pathways
BACKGROUND: Our previous work demonstrated that persistent peripheral nociception (PPN) leads to synaptic plasticity and functional changes in the rat hippocampus. The protein kinase mTOR is a critical regulator of protein synthesis-dependent synaptic plasticity in the hippocampus as well as synapti...
Autores principales: | Lyu, Dan, Yu, Wenli, Tang, Ning, Wang, Ruirui, Zhao, Zhenyu, Xie, Fang, He, Yongjin, Du, Hongyin, Chen, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892125/ https://www.ncbi.nlm.nih.gov/pubmed/24313960 http://dx.doi.org/10.1186/1744-8069-9-64 |
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