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SIRT1 Activating compounds reduce oxidative stress mediated neuronal loss in viral induced CNS demyelinating disease

BACKGROUND: Multiple sclerosis (MS) is characterized by central nervous system inflammation and demyelination, and increasing evidence demonstrates significant neuronal damage also occurs and is associated with permanent functional impairment. Current MS therapies have limited ability to prevent neu...

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Detalles Bibliográficos
Autores principales: Khan, Reas S, Dine, Kimberly, Das Sarma, Jayasri, Shindler, Kenneth S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892130/
https://www.ncbi.nlm.nih.gov/pubmed/24383546
http://dx.doi.org/10.1186/2051-5960-2-3