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SIRT1 Activating compounds reduce oxidative stress mediated neuronal loss in viral induced CNS demyelinating disease
BACKGROUND: Multiple sclerosis (MS) is characterized by central nervous system inflammation and demyelination, and increasing evidence demonstrates significant neuronal damage also occurs and is associated with permanent functional impairment. Current MS therapies have limited ability to prevent neu...
Autores principales: | Khan, Reas S, Dine, Kimberly, Das Sarma, Jayasri, Shindler, Kenneth S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892130/ https://www.ncbi.nlm.nih.gov/pubmed/24383546 http://dx.doi.org/10.1186/2051-5960-2-3 |
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