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Adoptive transfer of genetically engineered WT1-specific cytotoxic T lymphocytes does not induce renal injury

Because WT1 is expressed in leukemia cells, the development of cancer immunotherapy targeting WT1 has been an attractive translational research topic. However, concern of this therapy still remains, since WT1 is abundantly expressed in renal glomerular podocytes. In the present study, we clearly sho...

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Detalles Bibliográficos
Autores principales: Asai, Hiroaki, Fujiwara, Hiroshi, Kitazawa, Sohei, Kobayashi, Naoto, Ochi, Toshiki, Miyazaki, Yukihiro, Ochi, Fumihiro, Akatsuka, Yoshiki, Okamoto, Sachiko, Mineno, Junichi, Kuzushima, Kiyotaka, Ikeda, Hiroaki, Shiku, Hiroshi, Yasukawa, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892144/
https://www.ncbi.nlm.nih.gov/pubmed/24393438
http://dx.doi.org/10.1186/1756-8722-7-3