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Modification of the Drosophila model of in vivo Tau toxicity reveals protective phosphorylation by GSK3β
Hyperphosphorylation of the microtubule associated protein, Tau, is the hallmark of a group of neurodegenerative disorders known as the tauopathies which includes Alzheimer's disease. Precisely how and why Tau phosphorylation is increased in disease is not fully understood, nor how individual s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892155/ https://www.ncbi.nlm.nih.gov/pubmed/24429107 http://dx.doi.org/10.1242/bio.20136692 |