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Modification of the Drosophila model of in vivo Tau toxicity reveals protective phosphorylation by GSK3β

Hyperphosphorylation of the microtubule associated protein, Tau, is the hallmark of a group of neurodegenerative disorders known as the tauopathies which includes Alzheimer's disease. Precisely how and why Tau phosphorylation is increased in disease is not fully understood, nor how individual s...

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Detalles Bibliográficos
Autores principales:	Povellato, Giulia, Tuxworth, Richard I., Hanger, Diane P., Tear, Guy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892155/ https://www.ncbi.nlm.nih.gov/pubmed/24429107 http://dx.doi.org/10.1242/bio.20136692

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