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Nitrite impacts the survival of Mycobacterium tuberculosis in response to isoniazid and hydrogen peroxide
When access to molecular oxygen is restricted, Mycobacterium tuberculosis (Mtb) can respire an alternative electron acceptor, nitrate. We found that Mtb within infected primary human macrophages in vitro at physiologic tissue oxygen tensions respired nitrate, generating copious nitrite. A strain of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892337/ https://www.ncbi.nlm.nih.gov/pubmed/24019302 http://dx.doi.org/10.1002/mbo3.126 |