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Nitrite impacts the survival of Mycobacterium tuberculosis in response to isoniazid and hydrogen peroxide

When access to molecular oxygen is restricted, Mycobacterium tuberculosis (Mtb) can respire an alternative electron acceptor, nitrate. We found that Mtb within infected primary human macrophages in vitro at physiologic tissue oxygen tensions respired nitrate, generating copious nitrite. A strain of...

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Detalles Bibliográficos
Autores principales:	Cunningham-Bussel, Amy, Bange, Franz C, Nathan, Carl F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892337/ https://www.ncbi.nlm.nih.gov/pubmed/24019302 http://dx.doi.org/10.1002/mbo3.126

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