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Isocitrate dehydrogenase 2 mutation is a frequent event in osteosarcoma detected by a multi-specific monoclonal antibody MsMab-1

Somatic mutations of isocitrate dehydrogenase (IDH) 1 and IDH2 occur in gliomas, acute myeloid leukemia, and cartilaginous tumors. Somatic mosaic IDH1/2 mutations are also reported in Ollier disease and Maffucci syndrome, which are characterized by multiple central cartilaginous tumors. Although IDH...

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Detalles Bibliográficos
Autores principales: Liu, Xing, Kato, Yukinari, Kaneko, Mika Kato, Sugawara, Masato, Ogasawara, Satoshi, Tsujimoto, Yuta, Naganuma, Yasushi, Yamakawa, Mitsunori, Tsuchiya, Takashi, Takagi, Michiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892385/
https://www.ncbi.nlm.nih.gov/pubmed/24403254
http://dx.doi.org/10.1002/cam4.149