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Suppression of choriocarcinoma invasion and metastasis following blockade of BDNF/TrkB signaling

Brain-derived neurotrophic factor (BDNF) acts through its cognate receptor tyrosine kinase-B (TrkB) to regulate diverse physiological functions in reproductive and other tissues. In normal and malignant trophoblastic cells, the BDNF/TrkB signaling promotes cell growth. Due to the highly malignant na...

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Detalles Bibliográficos
Autores principales: Kawamura, Kazuhiro, Kawamura, Nanami, Okamoto, Naoki, Manabe, Motomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892389/
https://www.ncbi.nlm.nih.gov/pubmed/24403258
http://dx.doi.org/10.1002/cam4.158