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Ipilimumab and radiation therapy for melanoma brain metastases

Ipilimumab, an antibody that enhances T-cell activation, may augment immunogenicity of tumor cells that are injured by radiation therapy. We hypothesized that patients with melanoma brain metastasis treated with both ipilimumab and radiotherapy would have improved overall survival, and that the sequ...

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Detalles Bibliográficos
Autores principales: Silk, Ann W, Bassetti, Michael F, West, Brady T, Tsien, Christina I, Lao, Christopher D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892394/
https://www.ncbi.nlm.nih.gov/pubmed/24403263
http://dx.doi.org/10.1002/cam4.140