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Hepatic Fibrosis Inhibitory Effect of Peptides Isolated from Navicula incerta on TGF-β1 Induced Activation of LX-2 Human Hepatic Stellate Cells

In this study, novel peptides (NIPP-1, NIPP-2) derived from Navicula incerta (microalgae) protein hydrolysate were explored for their inhibitory effects on collagen release in hepatic fibrosis with the investigation of its underlying mechanism of action. TGF-β1 activated fibrosis in LX-2 cells was e...

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Detalles Bibliográficos
Autores principales: Kang, Kyong-Hwa, Qian, Zhong-Ji, Ryu, BoMi, Karadeniz, Fatih, Kim, Daekyung, Kim, Se-Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Food Science and Nutrition 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892505/
https://www.ncbi.nlm.nih.gov/pubmed/24471121
http://dx.doi.org/10.3746/pnf.2013.18.2.124