CD14 Mediates Binding of High Doses of LPS but Is Dispensable for TNF-α Production

Activation of macrophages with lipopolysaccharide (LPS) involves a sequential engagement of serum LPS-binding protein (LBP), plasma membrane CD14, and TLR4/MD-2 signaling complex. We analyzed participation of CD14 in TNF-α production stimulated with 1–1000 ng/mL of smooth or rough LPS (sLPS or rLPS)...

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Detalles Bibliográficos
Autores principales: Borzęcka, Kinga, Płóciennikowska, Agnieszka, Björkelund, Hanna, Sobota, Andrzej, Kwiatkowska, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892557/
https://www.ncbi.nlm.nih.gov/pubmed/24489448
http://dx.doi.org/10.1155/2013/824919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892557/
https://www.ncbi.nlm.nih.gov/pubmed/24489448
http://dx.doi.org/10.1155/2013/824919

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