In vitro anti-mycobacterial activity of (E)-N'-(monosubstituted-benzylidene) isonicotinohydrazide derivatives against isoniazid-resistant strains

A series of twenty-three N-acylhydrazones derived from isoniazid (INH 1-23) have been evaluated for their in vitro antibacterial activity against INH- susceptible strain of M. tuberculosis (RG500) and three INH-resistant clinical isolates (RG102, RG103 and RG113). In general, derivatives 4, 14, 15 a...

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Detalles Bibliográficos
Autores principales: Coelho, Tatiane S., Cantos, Jessica B., Bispo, Marcelle L.F., Gonçalves, Raoni S.B., Lima, Camilo H.S., da Silva, Pedro E.A., Souza, Marcus V. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892661/
https://www.ncbi.nlm.nih.gov/pubmed/24470920
http://dx.doi.org/10.4081/idr.2012.e13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892661/
https://www.ncbi.nlm.nih.gov/pubmed/24470920
http://dx.doi.org/10.4081/idr.2012.e13

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