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Topological augmentation to infer hidden processes in biological systems

Motivation: A common problem in understanding a biochemical system is to infer its correct structure or topology. This topology consists of all relevant state variables—usually molecules and their interactions. Here we present a method called topological augmentation to infer this structure in a sta...

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Detalles Bibliográficos
Autores principales: Sunnåker, Mikael, Zamora-Sillero, Elias, López García de Lomana, Adrián, Rudroff, Florian, Sauer, Uwe, Stelling, Joerg, Wagner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892687/
https://www.ncbi.nlm.nih.gov/pubmed/24297519
http://dx.doi.org/10.1093/bioinformatics/btt638