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PPARγ Agonist Rosiglitazone Suppresses Renal mPGES-1/PGE2 Pathway in db/db Mice

Evidence had shown the detrimental effect of prostaglandin (PG) E2 in diabetic nephropathy (DN) of STZ-induced type-1 diabetes but its role in the development of DN of type-2 diabetes remains uncertain. The present study was undertaken to investigate the regulation of PGE2 synthetic pathway and the...

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Detalles Bibliográficos
Autores principales: Sun, Ying, Jia, Zhanjun, Liu, Gang, Zhou, Li, Liu, Mi, Yang, Baoxue, Yang, Tianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892750/
https://www.ncbi.nlm.nih.gov/pubmed/24489534
http://dx.doi.org/10.1155/2013/612971