Long-Lasting T Cell-Independent IgG Responses Require MyD88-Mediated Pathways and Are Maintained by High Levels of Virus Persistence

Many viruses induce acute T cell-independent (TI) B cell responses due to their repetitive epitopes and the induction of innate cytokines. Nevertheless, T cell help is thought necessary for the development of long-lasting antiviral antibody responses in the form of long-lived plasma cells and memory...

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Detalles Bibliográficos
Autores principales: Raval, Forum M., Mishra, Rabinarayan, Garcea, Robert L., Welsh, Raymond M., Szomolanyi-Tsuda, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892782/
https://www.ncbi.nlm.nih.gov/pubmed/24194540
http://dx.doi.org/10.1128/mBio.00812-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892782/
https://www.ncbi.nlm.nih.gov/pubmed/24194540
http://dx.doi.org/10.1128/mBio.00812-13

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