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Gene expression profiling upon (212)Pb-TCMC-trastuzumab treatment in the LS-174T i.p. xenograft model

Recent studies have demonstrated that therapy with (212)Pb-TCMC-trastuzumab resulted in (1) induction of apoptosis, (2) G2/M arrest, and (3) blockage of double-strand DNA damage repair in LS-174T i.p. (intraperitoneal) xenografts. To further understand the molecular basis of the cell killing efficac...

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Detalles Bibliográficos
Autores principales: Yong, Kwon J, Milenic, Diane E, Baidoo, Kwamena E, Kim, Young-Seung, Brechbiel, Martin W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892796/
https://www.ncbi.nlm.nih.gov/pubmed/24403230
http://dx.doi.org/10.1002/cam4.132