Cargando…
Gene expression profiling upon (212)Pb-TCMC-trastuzumab treatment in the LS-174T i.p. xenograft model
Recent studies have demonstrated that therapy with (212)Pb-TCMC-trastuzumab resulted in (1) induction of apoptosis, (2) G2/M arrest, and (3) blockage of double-strand DNA damage repair in LS-174T i.p. (intraperitoneal) xenografts. To further understand the molecular basis of the cell killing efficac...
Autores principales: | Yong, Kwon J, Milenic, Diane E, Baidoo, Kwamena E, Kim, Young-Seung, Brechbiel, Martin W |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Science Inc
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892796/ https://www.ncbi.nlm.nih.gov/pubmed/24403230 http://dx.doi.org/10.1002/cam4.132 |
Ejemplares similares
-
Bench to Bedside: Stability Studies of GMP Produced Trastuzumab-TCMC in Support of a Clinical Trial
por: Milenic, Diane E., et al.
Publicado: (2015) -
Cell Killing Mechanisms and Impact on Gene Expression by Gemcitabine and (212)Pb-Trastuzumab Treatment in a Disseminated i.p. Tumor Model
por: Yong, Kwon Joong, et al.
Publicado: (2016) -
Safety and Outcome Measures of First-in-Human Intraperitoneal α Radioimmunotherapy With (212)Pb-TCMC-Trastuzumab
por: Meredith, Ruby F., et al.
Publicado: (2018) -
Toxicological Studies of (212)Pb Intravenously or Intraperitoneally Injected into Mice for a Phase 1 Trial
por: Milenic, Diane E., et al.
Publicado: (2015) -
(212)Pb-radioimmunotherapy potentiates paclitaxel-induced cell killing efficacy by perturbing the mitotic spindle checkpoint
por: Yong, K J, et al.
Publicado: (2013)