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Protein structure quality assessment based on the distance profiles of consecutive backbone Cα atoms

Predicting the three dimensional native state structure of a protein from its primary sequence is an unsolved grand challenge in molecular biology. Two main computational approaches have evolved to obtain the structure from the protein sequence - ab initio/de novo methods and template-based modeling...

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Detalles Bibliográficos
Autores principales: Chakraborty, Sandeep, Venkatramani, Ravindra, Rao, Basuthkar J., Asgeirsson, Bjarni, Dandekar, Abhaya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892923/
https://www.ncbi.nlm.nih.gov/pubmed/24555103
http://dx.doi.org/10.12688/f1000research.2-211.v3