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Protein structure quality assessment based on the distance profiles of consecutive backbone Cα atoms
Predicting the three dimensional native state structure of a protein from its primary sequence is an unsolved grand challenge in molecular biology. Two main computational approaches have evolved to obtain the structure from the protein sequence - ab initio/de novo methods and template-based modeling...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892923/ https://www.ncbi.nlm.nih.gov/pubmed/24555103 http://dx.doi.org/10.12688/f1000research.2-211.v3 |