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C/EBPα: critical at the origin of leukemic transformation

Acute myeloid leukemia (AML) is a hematopoietic malignancy characterized by clonal expansion of myeloid progenitor cells. A major mechanistic theme in AML biology is the extensive collaboration among fusion oncoproteins, transcription factors, and chromatin regulators to initiate and sustain a trans...

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Detalles Bibliográficos
Autores principales: Roe, Jae-Seok, Vakoc, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892974/
https://www.ncbi.nlm.nih.gov/pubmed/24395889
http://dx.doi.org/10.1084/jem.20132530