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Inflammation in rat pregnancy inhibits spiral artery remodeling leading to fetal growth restriction and features of preeclampsia

Fetal growth restriction (FGR) and preeclampsia (PE) are often associated with abnormal maternal inflammation, deficient spiral artery (SA) remodeling, and altered uteroplacental perfusion. Here, we provide evidence of a novel mechanistic link between abnormal maternal inflammation and the developme...

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Detalles Bibliográficos
Autores principales: Cotechini, Tiziana, Komisarenko, Maria, Sperou, Arissa, Macdonald-Goodfellow, Shannyn, Adams, Michael A., Graham, Charles H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892976/
https://www.ncbi.nlm.nih.gov/pubmed/24395887
http://dx.doi.org/10.1084/jem.20130295