Midline crossing and Slit responsiveness of commissural axons require USP33

Commissural axons cross the ventral midline of the neural tube in a Slit-dependent manner. The underlying molecular mechanisms remain to be elucidated. Here we report that the deubiquitinating enzyme USP33 interacts with the Robo1 receptor. USP33 is essential for midline crossing by commissural axon...

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Detalles Bibliográficos
Autores principales: Yuasa-Kawada, Junichi, Kinoshita-Kawada, Mariko, Wu, Guan, Rao, Yi, Wu, Jane Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893063/
https://www.ncbi.nlm.nih.gov/pubmed/19684588
http://dx.doi.org/10.1038/nn.2382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893063/
https://www.ncbi.nlm.nih.gov/pubmed/19684588
http://dx.doi.org/10.1038/nn.2382

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