MicroRNA-147 Induces a Mesenchymal-To-Epithelial Transition (MET) and Reverses EGFR Inhibitor Resistance

BACKGROUND: The epithelial-mesenchymal transition (EMT) is a key developmental program that is often activated during cancer progression and may promote resistance to therapy. An analysis of patients (n = 71) profiled with both gene expression and a global microRNA assessment (∼415 miRs) identified...

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Detalles Bibliográficos
Autores principales: Lee, Chang Gong, McCarthy, Susan, Gruidl, Mike, Timme, Cindy, Yeatman, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893127/
https://www.ncbi.nlm.nih.gov/pubmed/24454732
http://dx.doi.org/10.1371/journal.pone.0084597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893127/
https://www.ncbi.nlm.nih.gov/pubmed/24454732
http://dx.doi.org/10.1371/journal.pone.0084597

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