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MicroRNA-147 Induces a Mesenchymal-To-Epithelial Transition (MET) and Reverses EGFR Inhibitor Resistance
BACKGROUND: The epithelial-mesenchymal transition (EMT) is a key developmental program that is often activated during cancer progression and may promote resistance to therapy. An analysis of patients (n = 71) profiled with both gene expression and a global microRNA assessment (∼415 miRs) identified...
Autores principales: | Lee, Chang Gong, McCarthy, Susan, Gruidl, Mike, Timme, Cindy, Yeatman, Timothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893127/ https://www.ncbi.nlm.nih.gov/pubmed/24454732 http://dx.doi.org/10.1371/journal.pone.0084597 |
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