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Deriving a Mutation Index of Carcinogenicity Using Protein Structure and Protein Interfaces

With the advent of Next Generation Sequencing the identification of mutations in the genomes of healthy and diseased tissues has become commonplace. While much progress has been made to elucidate the aetiology of disease processes in cancer, the contributions to disease that many individual mutation...

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Detalles Bibliográficos
Autores principales: Espinosa, Octavio, Mitsopoulos, Konstantinos, Hakas, Jarle, Pearl, Frances, Zvelebil, Marketa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893166/
https://www.ncbi.nlm.nih.gov/pubmed/24454733
http://dx.doi.org/10.1371/journal.pone.0084598