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Deriving a Mutation Index of Carcinogenicity Using Protein Structure and Protein Interfaces
With the advent of Next Generation Sequencing the identification of mutations in the genomes of healthy and diseased tissues has become commonplace. While much progress has been made to elucidate the aetiology of disease processes in cancer, the contributions to disease that many individual mutation...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893166/ https://www.ncbi.nlm.nih.gov/pubmed/24454733 http://dx.doi.org/10.1371/journal.pone.0084598 |