Cargando…
Deriving a Mutation Index of Carcinogenicity Using Protein Structure and Protein Interfaces
With the advent of Next Generation Sequencing the identification of mutations in the genomes of healthy and diseased tissues has become commonplace. While much progress has been made to elucidate the aetiology of disease processes in cancer, the contributions to disease that many individual mutation...
Autores principales: | Espinosa, Octavio, Mitsopoulos, Konstantinos, Hakas, Jarle, Pearl, Frances, Zvelebil, Marketa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893166/ https://www.ncbi.nlm.nih.gov/pubmed/24454733 http://dx.doi.org/10.1371/journal.pone.0084598 |
Ejemplares similares
-
Comprehensive Genomic Analysis of a BRCA2 Deficient Human Pancreatic Cancer
por: Barber, Louise J., et al.
Publicado: (2011) -
MoKCa database—mutations of kinases in cancer
por: Richardson, Christopher J., et al.
Publicado: (2009) -
Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation
por: McDade, Simon S., et al.
Publicado: (2012) -
High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing
por: Sims, David, et al.
Publicado: (2011) -
Genomic distance entrained clustering and regression modelling highlights interacting genomic regions contributing to proliferation in breast cancer
por: Dexter, Tim J, et al.
Publicado: (2010)