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Prognostic Significance and Molecular Mechanism of ATP-Binding Cassette Subfamily C Member 4 in Resistance to Neoadjuvant Radiotherapy of Locally Advanced Rectal Carcinoma

BACKGROUND: Mechanism of radioresistance in rectal carcinoma remains largely unknown. We aimed to evaluate the predictive role of ATP-binding cassette subfamily C member 4 (ABCC4) in locally advanced rectal carcinoma and explore possible molecular mechanisms by which ABCC4 confers the resistance to...

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Detalles Bibliográficos
Autores principales: Yu, Zhiqi, Zhang, Chang, Chai, Rui, Du, Yan, Gao, Xianhua, Xing, Junjie, Yu, Enda, Zhang, Wei, Zhang, Xiaoqing, Cao, Guangwen, Fu, Chuangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893201/
https://www.ncbi.nlm.nih.gov/pubmed/24454870
http://dx.doi.org/10.1371/journal.pone.0085446