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EGFR, HER-2 and KRAS in Canine Gastric Epithelial Tumors: A Potential Human Model?
Epidermal growth factor receptor (EGFR or HER-1) and its analog c-erbB-2 (HER-2) are protein tyrosine kinases correlated with prognosis and response to therapy in a variety of human cancers. KRAS mediates the transduction of signals between EGFR and the nucleus, and its mutation has been identified...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893207/ https://www.ncbi.nlm.nih.gov/pubmed/24454858 http://dx.doi.org/10.1371/journal.pone.0085388 |