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Optimizing Viable Leukocyte Sampling from the Female Genital Tract for Clinical Trials: An International Multi-Site Study

BACKGROUND: Functional analysis of mononuclear leukocytes in the female genital mucosa is essential for understanding the immunologic effects of HIV vaccines and microbicides at the site of HIV exposure. However, the best female genital tract sampling technique is unclear. METHODS AND FINDINGS: We e...

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Detalles Bibliográficos
Autores principales: McKinnon, Lyle R., Hughes, Sean M., De Rosa, Stephen C., Martinson, Jeffrey A., Plants, Jill, Brady, Kirsten E., Gumbi, Pamela P., Adams, Devin J., Vojtech, Lucia, Galloway, Christine G., Fialkow, Michael, Lentz, Gretchen, Gao, Dayong, Shu, Zhiquan, Nyanga, Billy, Izulla, Preston, Kimani, Joshua, Kimwaki, Steve, Bere, Alfred, Moodie, Zoe, Landay, Alan L., Passmore, Jo-Ann S., Kaul, Rupert, Novak, Richard M., McElrath, M. Juliana, Hladik, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893217/
https://www.ncbi.nlm.nih.gov/pubmed/24454917
http://dx.doi.org/10.1371/journal.pone.0085675