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High throughput solution-based measurement of antibody-antigen affinity and epitope binning

Advances in human antibody discovery have allowed for the selection of hundreds of high affinity antibodies against many therapeutically relevant targets. This has necessitated the development of reproducible, high throughput analytical techniques to characterize the output from these selections. Am...

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Detalles Bibliográficos
Autores principales: Estep, Patricia, Reid, Felicia, Nauman, Claire, Liu, Yuqi, Sun, Tingwan, Sun, Joanne, Xu, Yingda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893237/
https://www.ncbi.nlm.nih.gov/pubmed/23575269
http://dx.doi.org/10.4161/mabs.23049