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Analysis of Novel NEFL mRNA Targeting microRNAs in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by progressive motor neuron degeneration and neurofilament aggregate formation. Spinal motor neurons in ALS also show a selective suppression in the levels of low molecular weight neurofilament (NEFL) mRNA. We have been interested...

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Detalles Bibliográficos
Autores principales: Ishtiaq, Muhammad, Campos-Melo, Danae, Volkening, Kathryn, Strong, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893244/
https://www.ncbi.nlm.nih.gov/pubmed/24454911
http://dx.doi.org/10.1371/journal.pone.0085653