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Aspergillus nidulans Cell Wall Composition and Function Change in Response to Hosting Several Aspergillus fumigatus UDP-Galactopyranose Mutase Activity Mutants

Deletion or repression of Aspergillus nidulans ugmA (AnugmA), involved in galactofuranose biosynthesis, impairs growth and increases sensitivity to Caspofungin, a β-1,3-glucan synthesis antagonist. The A. fumigatus UgmA (AfUgmA) crystal structure has been determined. From that study, AfUgmA mutants...

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Detalles Bibliográficos
Autores principales: Alam, Md Kausar, van Straaten, Karin E., Sanders, David A. R., Kaminskyj, Susan G. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893270/
https://www.ncbi.nlm.nih.gov/pubmed/24454924
http://dx.doi.org/10.1371/journal.pone.0085735